The term calcifying odontogenic cyst was first introduced by gorlin in 1962 eshghyar et al. Radicular cysts make around 5268% of all cysts affecting the human jaws. The computerized tomography in coronal plane revealed a hypodense lesion in the posterior. Adenomatoid odontogenic tumor aot mixed calcifying epithelial odontogenic tumor ceot calcifying odontogenic cyst gorlin cyst odontoma mixed lesion cementoblastoma. Odontogenic cysts and tumors ppt linkedin slideshare. Calcifying odontogenic cyst gorlins cyst report of two cases article pdf available in collegium antropologicum 281. Calcifying epithelial odontogenic tumour ceot is a rare benign odontogenic neoplasm, forming 0. Adenomatoid odontogenic tumor, calcifying odontogenic cyst, cysts, epithelialmesenchymal interaction, odontogenic neoplasm, periapical lesion.
Epidemiology most common odontogenic cyst is periapical. Calcifying epithelial odontogenic tumor ceot, also known as a pindborg tumor, previously has been called adenoid adamintoblastoma, unusual ameloblastoma and cystic odontoma is typically located in the premolar and molar region of the mandible, although up to a third are found in the maxilla. Review article a rare case of multilocalcalcifying. It is classified into two typestype ithe cystic variant, type iisolid. The most notable features of this pathologic entity are histopathological features which include a cystic lining demonstrating characteristic ghost epithelial cells with a propensity to calcify. Pdf calcifying odontogenic cyst gorlins cyst report. Teeth develop from budlike invagination of ectodermal lining of primitive oral cavity epithelium. The presence of mucous cells in the stratified squamous epithelium of dentigerous cyst is well documented.
Calcifying epithelial odontogenic tumor of the maxilla. Sep 30, 2012 lateral periodontal cyst glandular odontogenic cyst unclassified paradental cyst calcifying odontogenic cyst 9. Nov 25, 2010 calcifying epithelial odontogenic tumour ceot is a rare benign odontogenic neoplasm, forming 0. In onethird of cases, an impacted tooth is involved. Odontogenic cysts ioannis chatzistefanou, vassilios kogias and. Calcifying odontogenic cyst associated with ameloblastoma and adenomatoid odontogenic tumor old male patient with a large coc associated with an impacted 38 and involving the left body and angle of mandible. Dec 18, 2014 dentigerous cyst can be defined as an odontogenic cyst that surrounds the crown of an impacted tooth, caused by the fluid accumulation between the reduced enamel epithelium and the enamel surface. Has many features of odontogenic tumor, therefore it is placed in the category of tumors in the latest who classification of odontogenic cysts and tumors. Recurrent calcifying odontogenic cyst 145 have been reported in the literature, one by gorlin et al. Synchronization of calcifying odontogenic cyst and aneurysmal bone cyst.
Multilocalcalcifying epithelial odontogenic tumor 17080 int j clin exp med 2016. Calcifying epithelial odontogenic cyst associated with complex. Myxoma, and odontogenic fibroma are the commonest neoplasms. Calcifying odontogenic cyst gorlins cyst report of. The calcifying odontogenic cyst is an uncommon benign cyst of odontogenic origin, characterized by an ameloblastomalike epithelium with ghost cells that may. Calcifying odontogenic cyst article about calcifying. The calcifying epithelial odontogenic tumor ceot, also known as a pindborg tumor, is an odontogenic tumor first recognized by the danish pathologist jens jorgen pindborg in 1955.
It appears as a cyst lined by an ameloblastic epithelium, containing variable amounts of ghost cells and calcifications. The lesion is unusual in that it has some features of a cyst but also has many characteristics of a solid neoplasm cysts and tumors of odontogenic origin. The calcifying odontogenic cyst coc is a cystic lesion lined by an ameloblastomalike epithelium containing ghost cells and calcifications. On extraoral examination, no facial asymmetry was evident. Oral cavity cysts oral cavity cysts exist in jaw bones and soft tissue, gingiva odontogenic. Calcifying odontogenic cyst gorlin cyst ddmfr oral. Histologically, ccot is usually composed of a cystic cavity with fibrotic capsule lined by an odontogenic epithelium. Studart soares ec, gurgel costa fw, silveira esses df, alves filho ep, nunes alves apn. It was thoroughly described by gorlin and coworkers in 19621 and. Primary intraosseous carcinoma and odontogenic cyst. Histopathological examination of the hematoxylineosin hestained sections showed a cystic cavity lined by orthokeratinized stratified squamous epithelium. Jul 24, 2010 the world health organization classification of head and neck tumors classifies the lesion as an odontogenic tumor and names it calcifying cystic odontogenic tumor.
The calcifying epithelial odontogenic cyst ceoc is a developmental odontogenic cyst, which was first categorized as a distinct entity by gorlin in 1962. Since the original description of the calcifying odontogenic cyst by gorlin et al. Recurrent calcifying odontogenic cyst universiteit utrecht. Introduction calcifying odontogenic cyst coc or calcifying cystic odontogenic tumor ccot is one of the ghost cell odontogenic lesions that mostly grows as a cystic lesion. Calcifying odotogenic cyst is a benign odontogenic tumor of cystic type most likely to affect the anterior areas of the jaws. Odontogenic cyst and non odontogenic cyst epithelium.
Introduction a cyst is an epithelium lined sac containing fluid or semifluid material the epithelial cells first proliferate and later undergo degeneration and liquefaction grow by expansion, causing displacement of adjacent teeth 3. Lateral periodontal cyst glandular odontogenic cyst unclassified paradental cyst calcifying odontogenic cyst 9. It has been reported predominantly as an incidental. On radiographs, the calcifying odontogenic cyst appears as a unilocular radiolucency dark area. The world health organization classification of head and neck tumors classifies the lesion as an odontogenic tumor and names it calcifying cystic odontogenic tumor. Oct 16, 2010 the peripheral calcifying odontogenic cyst pcoc accounts for less than 25% of the cases of calcifying odontogenic cysts and most commonly appears as a nodule on the gingiva.
Odontogenic cyst and non odontogenic cyst epithelium anatomy. Odontogenic cysts oc are epithelial lined cystic lesions of the jaws. Odontogenic cyst are a group of jaw cysts that are formed from tissues involved in odontogenesis tooth development. Who defined it as a cystic lesion in which the epithelial lining shows a welldefined basal layer of columnar cells, an overlying layer that is often many cells thick and that may resemble stellate reticulum, and masses of ghost epithelial cells that may be in the epithelial cyst lining or in the fibrous. Non odontogenic jaw cysts are cysts arising from epithelial remnants of embryonic ducts left behind after embryonal facial and jaw development. Chronic osteomyelitis mixed florid cementoosseous dysplasia mixed fibrous dysplasia mixed cementoossifying fibroma 2nd stage paget disease. Calcifying epithelial odontogenic tumor, gingiva, and peripheral odontogenic tumor. The calcifying ghost cell odontogenic cyst cgcoc was first described by gorlin et al. Like other odontogenic neoplasms, it is thought to arise from the epithelial element of the enamel origin. Calcifying odontogenic cyst of anterior maxilla with complex. Glandular odontogenic cyst sialo odontogenic cyst very rare odontogenic ghost cell cyst or gorlin cyst.
Introduction a cyst is an epithelium lined sac containing fluid or semifluid material the epithelial cells first proliferate and later undergo degeneration and liquefaction grow by. Calcifying odontogenic cyst is a rare lesion of the jaws first described as a distinct entity by gorlin et al. Case report calcifying epithelial odontogenic tumor. Odontogenic cyst and non odontogenic cyst free download as powerpoint presentation. Calcifying epithelial odontogenic tumor an overview. Calcifying ghost cell odontogenic cyst is comparatively rare in occurrence, constituting about 0. In addition, the calcifying odontogenic cyst may be associated with other odontogenic tumors, most commonly odontoma. Pdf calcifying epithelial odontogenic cyst of the mandible.
An 11yearold female patient presented a swelling in the vestibular. History revealed that the swelling calcifying epithelial odontogenic cyst most often occurs as was initially small in size and had progressively increased to its a central intraosseous lesion, whereas peripheral extra present size. Soft tissue pathological changes are hyperplasias,inflammation and calcification are the common. No recurrence was observed during 57month followup. The pathological changes associated with the impacted 3rd molar are cystic changes which include dentigerous cysts, odontogenic keratocyst and calcifying odontogenic cyst. It is an unusual and unique lesion, which may show characteristics of. Calcifying odontogenic cyst with atypical features ncbi. It may be considered as a possible oral analogue of the calcifying epithelioma of malherbe pilomatrixoma occurring on skin, owing to the presence of ghost cell keratinization in both 2, 3, 4. It is an unusual and unique lesion, which may show characteristics of both a solid neoplasm and a cyst. The calcifying epithelial odontogenic tumor, also known as a pindborg tumor, is an odontogenic tumor first recognized by the danish pathologist jens jorgen pindborg in 1955.
Calcifying odontogenic cyst coc is an unusual and unique lesion with characteristics of a solid neoplasm and of a cyst. The following classification system is a modification of the world health organization. Most are harmless, but they should be removed when possible because they occasionally may change into malignant growths, become infected, or obstruct a gland. It is a typically benign and slow growing, but invasive neoplasm. Pdf calcifying odontogenic cyst or gorlin cyst, was first described by gorlin. Review article a rare case of multilocalcalcifying epithelial. In honour to this internationally renowned oral and maxillofacial pathologist, this tumor is also known as pindborgs tumour 4, 6.
Different manifestations of calcifying cystic 367 einstein. A majority of them are remnants of odontogenic apparatus. The most common odontogenic cyst reported is the radicular cyst. A calcifying epithelial odontogenic tumor ceot is a locally invasive epithelial neoplasm characterized by the development of intraepithelial structures, probably of an amyloidlike nature, which may become calcified and liberated as the cells break down. Mucous cells in the epithelial lining of dentigerous cyst. Comparison of components of odontogenic cyst fluids. Odontogenic cysts are closed sacs, and have a distinct membrane derived from rests of odontogenic epithelium. Odontogenic cyst definition of odontogenic cyst by medical. It was previously described as an adenoid adamantoblastoma, unusual ameloblastoma and a cystic odontoma. Calcifying odontogenic cyst gorlin cyst ddmfr oral and. Synchronization of calcifying odontogenic cyst and aneurysmal. Lateral periodontal cyst lpc is a relatively rare odontogenic pathology, representing about 0. A dentigerous cyst results because of the enlargement of the follicular space of the whole or part of the crown of an impacted or unerupted tooth and is attached to the neck of the tooth. Pdf calcifying odontogenic cyst gorlins cyst report of.
The calcifying cystic odontogenic tumor can occur in any location of the oral cavity and approximately 6567. The calcifying epithelial odontogenic tumor ceot is a rare benign epithelial odontogenic neoplasm of slow growth that is locally aggressive and tends to invade bone and adjacent soft tissue. It is most common in people in their second to third decades but can be seen at almost any age. Different manifestations of calcifying cystic odontogenic tumor. Pdf calcifying epithelial odontogenic cyst a case report. The calcifying odontogenic cyst coc is a developmental odontogenic cyst and its occurrence constitutes about 0. Calcifying odontogenic cyst was first described by gorlin et al.
Correct diagnosis and treatment should include a careful assessment of clinical, radiological and histopathological. Calcifying epithelial odontogenic tumor radiology reference. Calcifying epithelial odontogenic cyst associated with. Histological features of a calcifying odontogenic cyst with clusters of fusiform ghost cells and focal calcifications, lying in a stratified squamous epithelium 160 160. Who defined it as a cystic lesion in which the epithelial lining shows a welldefined basal layer of columnar cells, an overlying layer that is often many cells thick and that may resemble.
Here is reported the case of a 21yearold female patient with a ceot in the left mandibular posterior region. The lesion is unusual in that it has some features of a cyst but also has many characteristics of a solid neoplasm cysts and tumors of. Calcifying cystic odontogenic tumor a case report and. The microcysts subsequently collapse, merge and form a welldefined. Odontogenic cysts, tumors, and related jaw lesions preceptor.
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